Please use this identifier to cite or link to this item: https://hdl.handle.net/10419/300156 
Year of Publication: 
2024
Series/Report no.: 
IES Working Paper No. 16/2024
Publisher: 
Charles University in Prague, Institute of Economic Studies (IES), Prague
Abstract: 
This paper evaluates the cost-effectiveness of vaccinating women against human papillomaviruses (HPV) in the Czech Republic, where HPV is the main cause of most cervical carcinomas. It examines the cost-effectiveness of the current reimbursement policy for HPV vaccination compared to the suggested change. Using a homogeneous multistate Markov model, we approximate transitions among states that represent the progression stages of cervical carcinoma, utilizing healthcare reimbursement data from public health insurance. The analysis reveals that increasing immunization coverage from 65.8% to 80% is cost-effective, given the threshold of 1.2 million CZK per quality-adjusted life year. Similarly, expanding the eligible age for vaccination reimbursement from 13 to include ages 13 through 15 years, while also increasing coverage, results in comparable cost-effectiveness. Despite certain limitations, our findings suggest that enhancing the immunization coverage of HPV vaccination for women is economically justified. Consequently, we advocate for the implementation of the proposed policy modifications.
Subjects: 
Cost-effectiveness
Markov model
HPV
vaccination
cervical carcinoma
women
Czech Republic
JEL: 
I11
I13
I18
C61
Document Type: 
Working Paper

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